HOXD13 and neoplasm: Univariate and multivariate analysis showed that, together with gender, platelet count, MELD score, tumor size, tumor nodules, and vascular invasion, sPD-1 level was a significantly independent factor associated with the overal survival of HCC patients [HR (95%CI)= 1.622 (1.068-2.694), P= 0.026, Table 5].