No significant differences were observed in PD‐1 and PD‐L1 expressions among the types of mycoplasmosis with different clinical symptoms in the M. bovis‐infected cattle, although all of the median proportions of PD‐1+CD4+ (Fig. 3A), PD‐1+CD8+ (Fig. 3B), and PD‐L1+CD11b+CD14+ cells (Fig. 3C) were higher than those of healthy control cattle. The gene discussed is CD274; the disease is Mycoplasmoides infection.