Loss of E‐cadherin is observed in late‐stage malignant melanoma (Alexaki et al., 2010; Miller and Mihm, 2006) and the EMT‐inducing transcription factor network significantly changes during melanomagenesis and constitutes a risk factor for poor outcome in malignant melanoma (Caramel et al., 2013). The gene discussed is CDH1; the disease is melanoma.