The p62 status was significantly associated with synchronous liver metastasis (P = 0.033), but no significant association was detected between the p62 status and other factors such as patients' age, gender, tumor location, tumor size, histological differentiation, depth of invasion, lymph node metastasis, TNM stage, or Ki‐67 LI in this study. This evidence concerns the gene MKI67 and metastasis.