In this regard, the CXC motif chemokines GRO1/CXCL1, MIP-2α/CXCL2 and GRO3/CXCL3 were detected exclusively in platelets from dengue patients by proteome (orange in Fig 2B), suggesting that dengue infection may change platelet granule’s protein content through a more inflammatory profile. This evidence concerns the gene CXCL2 and dengue disease.