Conversely, total protein was increased in MetS rabbits at weeks 14 and 28 without changes in albumin, so this increase was probably due to an increase in globulins, some of which have been recently linked with the development of type 2 diabetes [27] and have been proposed as biomarkers for the development of liver fibrosis in non-alcoholic fatty liver disease [28]. The gene discussed is ALB; the disease is metabolic syndrome.