TNF and Huntington disease: A recent study showed associations of inflammatory biomarkers (hs-CRP, IL-6, tumor necrosis factor, soluble ICAM-1, soluble vascular cellular adhesion molecule 1) with CVD events and all-cause mortality in an incident HD population [34]; in that study, IL-6 was the only predictor of both CVD events and all-cause mortality in the study population [34].