The mRNA expression of the inflammatory cytokines, IL-6, IL-8 and IL-1ß, increased significantly following the 4 h exposure of HUVEC to HD patient's albumin (2.21 ± 0.16, 2.04 ± 0.12 and 1.97 ± 0.12-folds respectively), compared to HC albumin (Fig 3). The gene discussed is CXCL8; the disease is Huntington disease.