Except for a few chromosomal arms [gains of chr5p (which was present at 5 copies in SpT1, a tumor with 4 whole chr5), chr9p (5 copies in SpT4, a tumor with 3 whole chr9), and chr9q (5 copies in SpT6, a tumor with 4 whole chr9) (S3 Fig), and losses of chr19q in SpT4 and chrXq in SpT6; (S2A Table; for breakpoint details see S2B Table)], the observed copy number variations involve whole-chromosomes. Here, SPTLC1 is linked to neoplasm.