At 12 months post-enrollment, predicted means from sex-, age-, time on ART- and baseline weight-adjusted linear mixed models estimated that participants with hookworm infection had an average of 361 CD4+ cells/mcL (95%CI 310, 412) versus an average of 419 cells/mcL (95%CI 391, 448) amongst those without hookworm infection at baseline. Here, CD4 is linked to ancylostomiasis.