JAK/STAT signaling is highly conserved between Drosophila and mammals, both structurally and functionally,13 and its misregulation has important implications in human health.14, 15 In the adult Drosophila ovary, JAK/STAT activity within the somatic monolayered follicular epithelium surrounding each germline cyst has been shown to control several epithelial morphogenetic events. This evidence concerns the gene SOAT1 and cyst.