HMGCR and prostate carcinoma: Interestingly, HMGCR was recently shown as a potential target for cancer treatment.7, 8, 14 Indeed, it was demonstrated that highly proliferative cells were killed more efficiently with lower statin doses, as compared with non-proliferating cells.11 Furthermore, a recent study showed reduced mortality in patients with lung, bowel, breast or prostate cancer who were also diagnosed with hyperlipidaemia.15 The authors suggest that medication, such as statins, led to this outcome.