LAP3 and amyloidosis: Evidence from work carried out on amyloid β peptides in Alzheimer’s brains, identifies peptidase and protease mediated cleavage as a possible clearance mechanism in the catabolism of amyloid plaques (Matsumoto et al., 1995; Ogawa et al., 2000; Hersh, 2003; Malito et al., 2008).