In addition to direct epigenetic suppression of the THAP10 gene via methylation of its promoter by AML1‐ETO, a question then arose whether this represents the sole mechanism for AML1‐ETO to inhibit THAP10 expression or whether other mechanism(s) could also be involved in suppression of THAP10 expression in AML‐ETO+ AML. Here, RUNX1 is linked to acute myeloid leukemia.