Knowing this, the inhibition of these enzymes is as a promising strategy against cancer, and various studies have shown that flavonoids are capable of inhibiting a number of protein kinases from differing cellular signal pathways, such as: tyrosine kinase (PTK), serine/threonine kinases, and phosphatidylinositol 3-kinase (PI3K) [37]. The gene discussed is MARK2; the disease is cancer.