IGFBP3 and neoplasm: The fact that Fibroblast Growth Factor (FGF), Vascular Endothelial Growth Factor (VEGF), Transforming Growth Factor β (TGF β), and Stem Cell Factor (SCM) are increased in pterygial tissue [8,9,10], while IGFBP3 is decreased, further suggests that growth proliferation is not controlled in the same way as in tumor cells and, as a consequence, that pterygium is not neoplasia.