DRD2 and 22q11.2 deletion syndrome: To test whether abnormal elevation of Drd2s in the auditory thalamus is sufficient to cause behavioral and synaptic deficits in 22q11DS mice, we infected auditory thalamic neurons of WT mice with recombinant adeno-associated viruses (AAVs) encoding Drd2 and GFP (AAV-Drd2-GFP).