In addition, based on the outlier analysis from the Oncomine database (https://www.oncomine.org/), many more cancers, including Esophageal cancer, Ovarian cancer, Sarcoma, and Kidney cancer, have a portion of samples showing significantly higher expression of APLP1 in multiple studies, suggesting APLP1 may play an important role in some subtypes of cancers during tumorigenesis. Here, APLP1 is linked to esophageal cancer.