Even though most cytokine levels did not differ significantly between AC and SCC, different expression of several cytokines may indicate the biological diversity of the two types, as the median concentration of IL-1ra, IL-12, IL-17, FGFb, Mip-1α and Rantes in the serum and TNFα in the tumor tissue differed between the two entities AC and SCC, indicating biological differences. This evidence concerns the gene IL17A and neoplasm.