TPBG and neoplasm: Because we have detected some cross-reactivity of h5T4-specific T cells with the murine antigen, in that they can recognise antigen-presenting cells loaded with the murine 5T4 peptide pool in ex vivo IFN-γ Elispot (Figure 2B), we next tested whether strong immunity against h5T4 antigen and T cell cross-reactivity are sufficient for controlling outgrowth of m5T4-positive tumours.