We analyzed the expression levels of ITGB1 in data of GSE41445 and found that ITGB1 had the highest expression level in two NSCLC cell lines (incluing lung adenocarcinoma cell A549 and large cell lung cancer cell NCI-H460) (Figure 2A), suggesting that ITGB1 may play an important role in tumorigenesis and progress of lung cancer. Here, ITGB1 is linked to lung large cell carcinoma.