ITGB1 and squamous cell lung carcinoma: Next, we downloaded a microarray profiles data (GSE67061-GPL6480) from GEO database, which including 8 cases of immortalized human bronchial epithelial cell lines (BEC) and 69 cases of lung squamous cell carcinoma tissues (LSCC) and found that expression of ITGB1 was also significantly increased in LSCC when compared with that in BEC controls (FC = 1.8, P = 0.007; Figure 2C).