ITGB1 and metastatic malignant neoplasm in the lymph nodes: All 134 patients of NSCLC included in this study demonstrated that ITGB1 expression levels were positively correlated with lymph-node metastasis (P = 0.036), TNM stage (P = 0.042) and the diameter of the tumor (P = 0.044) as shown in Table 1.