The SMR analysis identified two potential causal genes, CDC42 (rs2268177; PSMR=1.07 × 10−12) and VEZT (rs14121; PSMR=3.41 × 10−6), underlying endometriosis loci at 1p36.12 and 12q22, respectively (Supplementary Data 14). Here, CDC42 is linked to endometriosis.