Furthermore, we also reported that pituitary tumor transforming gene 1 (PTTG1) [24], DNA fragmentation factor 45 (DFF45) [25], NOTCH1 [15], VEGF-C [16], and DROSHA [26] may be prognostic markers of ESCC. The gene discussed is PTTG1; the disease is esophageal squamous cell carcinoma.