However, low AGE diets were associated with an increased AGER1 only in T2DM patients (MD 96 mRNA, 95% CI 46 to 146) but not in non-T2DM (MD −20 mRNA, 95% CI −12 to 72) with no difference in AGER1 by dietary AGE content (Supplemental Table 3). This evidence concerns the gene DDOST and type 2 diabetes mellitus.