Moreover, several recent publications proposed that LINC00152 regulated the expression of genes involved in cell proliferation and migration pathways including E-Cadherin in the gastric cancer cell lines HGC-27 and SGC-790137, EpCAM in HepG2 and MHCC-97H cells derived from hepatocellular carcinoma38, EGFR in the gastric cancer cells MGC803 and HGC-2739, p15 and p21 in BGC-823 and SGC-7901 cells derived from gastric cancer40, mTOR, GOLPH3, KIF14, PRKCA and SMYD3 in the breast cancer cell line MDA-MB-23141, as well as miR-193a-3p and ERBB4 in the colon cancer cell lines SW620 and HT2942. The gene discussed is SMYD3; the disease is malignant colon neoplasm.