The involvement of HGF signaling, through its proto-oncogene receptor c-MET, is reported in the loss of epithelial phenotype and the acquisition of a migratory phenotype of non-cancerous cells as crucial event in the acquisition of a neoplastic phenotype, and it is widely documented in the progression of different types of cancer [12,14,15,16,17,18,19,20,21,22]. Here, HGF is linked to cancer.