Inflammatory macrophages attract natural killer (NK) cells and dendritic cells (DCs) to the tumor site through expression of chemokines CCL20, CXCL10 and CXCL11 while macrophage secretion of IFNα and IL-12 activates NK cells and DCs; activated NK cells and DCs in turn secrete IFNγ, interleukin (IL)-12 and IL-15 which promote pro-inflammatory macrophage, NK cell, and DC activation [4]. The gene discussed is CXCL10; the disease is neoplasm.