While TGFβ-expressing macrophage infiltration correlates with poor prognosis in pancreatic carcinomas, the epithelial-mesenchymal transition by E-cadherin displacement of TGFβ stimulation exposes Nectin-1, which increases oHSV entry in pancreatic cancer cells [41]. This evidence concerns the gene TGFB1 and exocrine pancreatic carcinoma.