Another oncolytic vaccinia virus, GLV-1h68, was associated with increased NK and macrophage infiltration and increased levels of many pro-inflammatory cytokines and chemokines involved in both antiviral and anti-tumor immune response (GCP-2, KC/GROα, IFNγ, CXCL10, IL-3, IL-6, Lymphotactin, M-CSF1, MIP-1β, MCP-1, MCP-3, MCP-5, RANTES) [39]. The gene discussed is IFNG; the disease is neoplasm.