Another hCFP, GrBR201K-αEpCAM(scFv), was designed by combining with the mutant R201K-GrB an antibody fragment against the epithelial cell adhesion molecule (EpCAM), a transmembrane glycoprotein mediating epithelial cell-cell adhesion which is expressed in triple negative breast cancers (TNBC) associated with an unfavorable prognosis [139]. Here, EPCAM is linked to triple-negative breast carcinoma.