CXCL10 and neoplasm: MV engineered to express IFNβ did induce two- to four-fold higher infiltration of CD68 monocytes in athymic mice bearing mesothelioma tumors compared to parent virus, demonstrating that the IFNβ transgene may play a therapeutic role in stimulating innate immune responses in the tumor microenvironment; however, CXCL10 production was not assayed [17].