Three eyes were highly suspicious for an endophthalmitis after injection and were treated with vitrectomy and intravitreal application of antibiotics, four eyes were highly suspicious for retinal pigment epithelial tear, one eye (AG) showed a submacular hemorrhage and was treated with vitrectomy and subretinal application of recombinant tissue plasminogen activator (rtPA). The gene discussed is PLAT; the disease is endophthalmitis.