ADA and hyperthyroidism: In a prior work, based on results obtained using the correction procedure being a part of our new method (see Section 4), we proposed a new, thyroid hormone-sensitive effect of adenosine deaminase inhibition, i.e., inhibition of adenosine deaminase appeared to increase the signal amplification of the atrial A1 adenosinergic system, an effect that was more pronounced in hyperthyroidism (in this investigation, no irreversible A1 receptor antagonist was administered) [32].