We also observed that a portion of USP13 was colocalized with STING at the ER without infection and HSV-1 infection resulted in STING disassociation from USP13 and redistribution in the cytoplasm (Supplementary Fig. 1b), consistent with previous observations that STING migrates out of ER after HSV-1 infection34. The gene discussed is STING1; the disease is infection.