LDLR and hepatocellular carcinoma: In vitro studies on human and mouse hepatoma cells have shown that a large number of miRs, including miR-27a, miR-27b, miR-185, miR-148a, miR-128-1, miR-130b, and miR-301b, can directly modulate LDLR expression through post-transcriptional regulation via targeting the 3’ UTR of LDLR [56–60] (Table 1).