Numerous studies have indicated that significant alterations in serotonin, dopamine and norepinephrine neurotransmitter metabolism and activation of a pro-inflammatory cytokine network are involved in psychiatric disorders associated with IFN-α (Widner et al., 2000; Raison et al., 2005b; Neurauter et al., 2008; Capuron et al., 2011). Here, IFNA2 is linked to psychiatric disorder.