Potential aspects for BRMS1-mediated metastasis suppression in breast cancers might be through altering metastasis-associated microRNA and/or interfering with specific cellular pathways relative to metastasis including: gap junctions, nuclear factor kappa B signaling, phosphoinositide signaling, cell motility and invasion, apoptosis, and tumor cell dissemination, though the exact mechanisms remain elucidated [30–36]. The gene discussed is BRMS1; the disease is breast carcinoma.