BRMS1 and neoplasm: This meta-analysis also indicated that expression of BRMS1 mRNA was adversely associated with TNM stage and tumor size (TNM stage: OR = 1.65, 95%CI = 0.36–2.93, P=0.012; tumor size: OR = −0.30, 95%CI = −0.55–0.05, P=0.020), while association with LNM status (OR = −1.69, 95%CI = −3.59–0.22, P=0.083) (Figure 4) proved nonexistent.