There was heterogeneity in expression of BRMS1 mRNA in LNM and TNM stage, thus random-effects model was performed (LNM: P < 0.001, I2 = 97.2%; TNM stage: P = 0.003, I2 = 88.7%), while showing no heterogeneity in tumor size, and thereby requiring use of a fixed-effect model (P = 0.697, I2 = 0%). This evidence concerns the gene BRMS1 and neoplasm.