In conclusion, a significant difference in the OS and RFS between patients with BRMS1+ and BRMS1−suggests that the BRMS1 protein might be a potential prognostic indicator in breast cancer, which is consistent with a study reported by Hanker et al. which determined that low BRMS1 mRNA expression and poor prognosis of breast cancer were indeed related [42]. This evidence concerns the gene BRMS1 and breast cancer.