However, the finding of multiple patients with CD in the same family is quite an infrequent phenotype: only 7.9% of the AIP mutation-negative FIPA families include CD, and only 1.4% of the families are ‘homogeneous’ for corticotropinomas (Hernández-Ramírez et al. 2015). The gene discussed is AIP; the disease is ACTH-producing pituitary gland adenoma.