ANXA5 and hepatocellular carcinoma: According to results of viability assay (Figure 1) and Annexin V-staining (Figure 6), we noted that both HCC cell lines were sensitive to a low dose 0.5 μM of 4-HPPP; however, a drug resistance of Ha22T was observed at the dose of 1 μM compared to Huh7 cells.