CCL2, CCL5 and CCL7 have been associated with skin inflammatory responses in general, regulating attraction of monocytes/macrophages, T cells or eosinophils, while CCL17 and CCL20 have been shown to be primarily involved in Th2 responses and AD, or Th17 responses and psoriasis, respectively36, 37. This evidence concerns the gene CCL5 and Alzheimer disease.