CXCR2 and infection: The CXC chemokine receptor 2 (CXCR2), highly expressed on neutrophils, recognizes chemokines produced at the site of infection and plays an important role in antimicrobial host defenses, such as neutrophil activation and chemotaxis (Sekido et al., 1993; Chuntharapai et al., 1994; Eisele et al., 2011).