KIR3DL1 and acute myeloid leukemia: NK cell killing of AML blasts in vitro is to a large extent dependent on intact expression of NKp46 and other NCRs.6 We and others have shown that expression levels of NCRs impact on relapse risk, suggesting NK cell function to be relevant to clinical outcome in AML.5, 32, 33 We thus sought to clarify whether the benefit of NCR expression was influenced by KIR and HLA genotypes.