An example of overlapping mQTL and eQTL signals for RNASET2 (MIM: 612944) on chromosome 6 is presented in Figure 1; both RNASET2 expression (SMR p = 6.04 × 10−8) and DNA methylation at two CpG sites in the first intron of the gene (cg25258033: SMR p = 2.84 × 10−10; cg25258033: SMR p = 2.50 × 10−10) are associated with Crohn disease (MIM: 266600). The gene discussed is RNASET2; the disease is Crohn disease.