In the progr-T1D group, 19 (82.6%) children were positive to •OH-INS-Ab, 18 (78.3%) to GADA, 16 (69.5%) to IA-2A, 10 (55.5%) to IAA and 6 (50%) to ZnT8A (Fig. 3e–h). The gene discussed is INS; the disease is type 1 diabetes mellitus.