Differential expression of UCH-L1, MAP1B, MAP2, VCAN, CDK4 and PDX-1 was verified in more than 40 PNETs, including insulinomas and non-insulinomas by IHC but the expression of CaSR was only validated in 29 insulinomas (Supplementary Table S4 and Fig. 2). This evidence concerns the gene CDK4 and pancreatic insulinoma.