CP and asthma: In regard to the involvement of CP in asthma pathogenesis, the controversy of whether the association is causal or coincidental can be settled in two ways: (1) patients diagnosed with asthma can be treated with the aim of evaluating the effects of antibiotics in ameliorating asthma symptoms compared to untreated of placebo controls and (2) animal models can be performed to evaluate the role of CP in asthma initiation and/or exacerbation.