There is little data on the role ADTG in PCOS and androgen metabolism, however this study showing the increased ADTG: DHEAS ratio in obese PCOS using state of the art measurement free from assay interference addresses the discrepancy noted in one study that it was not correlated with PCOS [8, 18], and with another suggesting that ADTG levels are increased [13]. The gene discussed is SULT2A1; the disease is polycystic ovary syndrome.