BRCA2 and neoplasm: The subset of somatic mutations had an 83% biallelic inactivation rate (of 20 somatic mutations, 18 were called by SGZ and 15 demonstrated biallelic inactivation), with intact copies of BRCA2 in a tumor with a heterozygous mutation (patient AZ-19-4449) and two tumors which harbored subclonal somatic mutations (Supplemental Table 1).