SULF2 and neoplasm: Using data mining from published transcriptomic datasets of UBUCs (GSE31684 and GSE32894), SULF1 and SULF2 were identified as significant genes showing upregulation during tumor progression among those associated with the heparan sulfate proteoglycan metabolic process (GO:0030201) (Figure 1, Supplementary Figure 1 and Table 1, Supplementary Table 1).