In addition to anticancer properties, several HDAC inhibitors (HDACi) including trichostatin A (TSA) have been found to exhibit good therapeutic efficacy in SLE murine models by downregulating IL-12, IFN-γ, IL-6, and IL-10 mRNA and protein levels in splenocytes as well as by reducing renal injury [17–19]. This evidence concerns the gene HDAC9 and systemic lupus erythematosus.