REST and cancer: Particularly, skipping of exon‐3 (∆E3), a common splicing event which eliminates ZF‐5 critical for REST nuclear targeting, is linked to cancer and modulated by pioglitazone—a highly selective activator of the peroxisome proliferator‐activated receptor gamma (PPARγ) exerting biological actions overlapping with REST 15, 16, 17.