GABRP and ovarian cancer: Previously, we performed genome-wide DNA methylation profiling using CpG methylation microarrays to examine the alterations in DNA methylation between metastatic tissues from ovarian cancer xenograft mice and ovarian carcinoma cells.5, 6, 7 Using these data, we identified two CpG sites within the GABRP promoter region that were clearly hypomethylated in all tested metastatic tissues compared with those of the ovarian carcinoma cells.